PDE4B-IN-7 is a potent inhibitor of phosphodiesterase-4B (PDE-4B) with an IC50 value of 160 nM, demonstrating strong and stable binding at its active site. This compound effectively inhibits acetylcholine-induced bronchospasm in guinea pigs, making it a valuable tool for asthma research. Additionally, PDE4B-IN-7 exhibits antimicrobial activity against both susceptible Gram-positive and Gram-negative bacterial strains, supporting its application in studies related to respiratory diseases and bacterial infections.
PDE4B-IN-7 is a potent inhibitor of phosphodiesterase-4B (PDE-4B) with an IC50 value of 160 nM, demonstrating strong and stable binding at its active site. This compound effectively inhibits acetylcholine-induced bronchospasm in guinea pigs, making it a valuable tool for asthma research. Additionally, PDE4B-IN-7 exhibits antimicrobial activity against both susceptible Gram-positive and Gram-negative bacterial strains, supporting its application in studies related to respiratory diseases and bacterial infections.
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