PDE4B modulator-1

Catalog No.: A41924
PDE4B Modulator
PDE4B modulator-1 is a selective modulator of phosphodiesterase 4B (PDE4B), targeting intracellular signaling pathways. It exhibits significant inhibition of PDE4B activity, leading to increased cAMP levels and subsequent regulation of various cellular processes. This compound is valuable for research in neurobiology, inflammation, and respiratory diseases, providing insights into PDE4B's role in mediating inflammatory responses and neuronal signaling.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPDE4B modulator-1 is a selective modulator of phosphodiesterase 4B (PDE4B), targeting intracellular signaling pathways. It exhibits significant inhibition of PDE4B activity, leading to increased cAMP levels and subsequent regulation of various cellular processes. This compound is valuable for research in neurobiology, inflammation, and respiratory diseases, providing insights into PDE4B's role in mediating inflammatory responses and neuronal signaling.
Product Information
Catalog NumA41924
FormulaC24H26N6O2S
Molecular Weight462.57
CAS Number848057-26-1
SMILESCC1(C)CC2=C(C3=NC=NC(NCC4=CC=CN=C4)=C3S5)C5=NC(N6CCOCC6)=C2CO1
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