PDE5-IN-15 is a xanthine derivative functioning as a selective inhibitor of phosphodiesterase type 5 (PDE5). With IC50 values of 0.002 μM against human PDE5, 0.180 μM against bovine PDE6, and 2.85 μM against bovine PDE1, this compound demonstrates potent activity. PDE5-IN-15 exhibits promising oral bioavailability in canines, making it a valuable tool for research on male erectile dysfunction and related therapeutic applications.
PDE5-IN-15 is a xanthine derivative functioning as a selective inhibitor of phosphodiesterase type 5 (PDE5). With IC50 values of 0.002 μM against human PDE5, 0.180 μM against bovine PDE6, and 2.85 μM against bovine PDE1, this compound demonstrates potent activity. PDE5-IN-15 exhibits promising oral bioavailability in canines, making it a valuable tool for research on male erectile dysfunction and related therapeutic applications.
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