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Biological Activity
Pelitrexol is a GARFT inhibitor, and is also a water soluble antifolate with anti-proliferative activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.57 mL | 107.87 mL | 215.75 mL |
| 0.5 mM | 4.31 mL | 21.57 mL | 43.15 mL |
| 1 mM | 2.16 mL | 10.79 mL | 21.57 mL |
| 5 mM | 0.43 mL | 2.16 mL | 4.31 mL |
*The above data is based on the productmolecular weight 463.5074. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17217 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 446022-33-9 |
| Formula | C20H25N5O6S |
| M. Wt | 463.5074 |
| Purity | >98% |
| Synonyms | AG 2037, AG2037 |
| SMILES | O=C(O)[[email protected]@H](NC(C1=CC(C)=C(CC[[email protected]](CN2)CC3=C2N=C(N)NC3=O)S1)=O)CCC(O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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