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PEN (rat)

Catalog No.: A60396
GPR83 Ligand
PEN (rat) is a potent endogenous ligand for the GPR83 receptor, primarily identified in the hypothalamic region. This neuropeptide, derived from the proprotein ProSAAS, plays a critical role in neuroendocrine regulation and appetite control. It is valuable for research focusing on metabolic disorders and neuropeptide signaling pathways.
PEN (rat) 569364-13-2 GPR83 Ligand
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Size Price Stock Qty
1mg
$50.00
In stock
5mg
$125.00
In stock
10mg
$210.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPEN (rat) is a potent endogenous ligand for the GPR83 receptor, primarily identified in the hypothalamic region. This neuropeptide, derived from the proprotein ProSAAS, plays a critical role in neuroendocrine regulation and appetite control. It is valuable for research focusing on metabolic disorders and neuropeptide signaling pathways.
Product Information
Catalog NumA60396
FormulaC102H169N27O33
Molecular Weight2301.59
CAS Number569364-13-2
SequenceAla-Val-Asp-Gln-Asp-Leu-Gly-Pro-Glu-Val-Pro-Pro-Glu-Asn-Val-Leu-Gly-Ala-Leu-Leu-Arg-Val
Sequence shorteningAVDQDLGPEVPPENVLGALLRV
SMILESC(=O)([C@H]1N(C([C@@H](NC([C@@H](NC(=O)[C@H]2N(C(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](C)N)=O)C(C)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC(O)=O)=O)CC(C)C)=O)=O)CCC2)CCC(O)=O)=O)[C@@H](C)C)=O)CCC1)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](C)C)C(O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(C)C)=O)C)=O)=O)CC(C)C)=O)C(C)C)=O)CC(N)=O)=O)CCC(O)=O)=O)CCC3
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Endocrinology-Hormones > GPR