PF-04447943

Catalog No.: A13121

PDE9 inhibitor

PF-04447943

PF-04447943 Chemical Structure

CAS NO. 1082744-20-4

PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor that increased indicators of hippocampal synaptic plasticity and improved cognitive function in a variety of cognition models in both rats and mice.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $145.00

Special Price $116.00

10 mg

Regular Price: $260.00

Special Price $208.00

25 mg

Regular Price: $550.00

Special Price $440.00

50 mg

Regular Price: $890.00

Special Price $712.00

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Biological Activity

PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor that increased indicators of hippocampal synaptic plasticity and improved cognitive function in a variety of cognition models in both rats and mice.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.29 mL 126.44 mL 252.87 mL
0.5 mM 5.06 mL 25.29 mL 50.57 mL
1 mM 2.53 mL 12.64 mL 25.29 mL
5 mM 0.51 mL 2.53 mL 5.06 mL

*The above data is based on the productmolecular weight 395.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13121
Actions Inhibitor
CAS No. 1082744-20-4
Formula C20H25N7O2
M. Wt 395.46
Purity >98%
Synonyms PF04447943, PF 04447943
SMILES C[[email protected]@H]1CN(C[[email protected]]1C2=NC(=O)C3=CNN(C3=N2)C4CCOCC4)CC5=NC=CC=N5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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