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|Storage||at -20°C 3 years Powder|
|Synonyms||PF04447943, PF 04447943|
|SMILES code||C[[email protected]@H]1CN(C[[email protected]]1C2=NC(=O)C3=CNN(C3=N2)C4CCOCC4)CC5=NC=CC=N5|
|PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor that increased indicators of hippocampal synaptic plasticity and improved cognitive function in a variety of cognition models in both rats and mice.|
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||25.29 mL||126.44 mL||252.87mL|
|0.5 mM||5.06 mL||25.29 mL||50.57 mL|
|1 mM||2.53 mL||12.64 mL||25.29 mL|
|5 mM||0.51 mL||2.53 mL||5.06 mL|
*The above data is based on the productmolecular weight 395.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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