PF-04449613

Catalog No.: A41801
PDE9A Inhibitor
PF-04449613 is a selective inhibitor of phosphodiesterase 9A (PDE9A), exhibiting an IC50 of 22 nM. This compound has demonstrated the ability to enhance motor learning in murine models, making it a valuable tool for investigating cognitive and neuropsychological processes. PF-04449613 is suitable for research applications focused on neurodegenerative diseases and cognitive disorders.
Grouped product items
Size Price Stock Qty
5mg
$85.00
In stock
10mg
$155.00
In stock
25mg
$345.00
In stock
50mg
$590.00
In stock
100mg
$1,010.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPF-04449613 is a selective inhibitor of phosphodiesterase 9A (PDE9A), exhibiting an IC50 of 22 nM. This compound has demonstrated the ability to enhance motor learning in murine models, making it a valuable tool for investigating cognitive and neuropsychological processes. PF-04449613 is suitable for research applications focused on neurodegenerative diseases and cognitive disorders.
Product Information
Catalog NumA41801
FormulaC21H25N5O3
Molecular Weight395.45
CAS Number1236858-52-8
SMILESO=C1C2=C(NC([C@H](N3CC(C3)OC4=CC=CC=C4)C)=N1)N(C5CCOCC5)N=C2
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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