PF-04937319

Catalog No.: A13154

glucokinase activator

PF-04937319

PF-04937319 Chemical Structure

CAS NO. 1245603-92-2

PF-04937319 is a glucokinase activator (GKA) with EC50 value of 154.4 ?μM, one of the most promising strategies for the treatment of type 2 diabetes mellitus.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $63.00

Special Price $50.40

5 mg

Regular Price: $189.00

Special Price $151.20

10 mg

Regular Price: $322.00

Special Price $257.60

50 mg

Regular Price: $966.00

Special Price $772.80

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-04937319 is a glucokinase activator (GKA) with EC50 value of 154.4 ?μM, one of the most promising strategies for the treatment of type 2 diabetes mellitus.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.13 mL 115.63 mL 231.25 mL
0.5 mM 4.63 mL 23.13 mL 46.25 mL
1 mM 2.31 mL 11.56 mL 23.13 mL
5 mM 0.46 mL 2.31 mL 4.63 mL

*The above data is based on the productmolecular weight 432.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13154
Actions Activator
CAS No. 1245603-92-2
Formula C22H20N6O4
M. Wt 432.43
Purity >98%
Synonyms PF04937319, PF 04937319
SMILES O=C(C1=NC=C(OC2=C3C=C(C)OC3=CC(C(NC4=NC=C(C)N=C4)=O)=C2)C=N1)N(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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