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Biological Activity
PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.73 mL | 113.65 mL | 227.3 mL |
| 0.5 mM | 4.55 mL | 22.73 mL | 45.46 mL |
| 1 mM | 2.27 mL | 11.37 mL | 22.73 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.55 mL |
*The above data is based on the productmolecular weight 439.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12608 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1469284-78-3 |
| Formula | C22H26ClN7O |
| M. Wt | 439.94 |
| Purity | >98% |
| Synonyms | PF06424439, PF 06424439 |
| SMILES | O=C([C@H]1CN(C2=CC=C3C(NC(C4(N5N=CC(Cl)=C5)CC4)=N3)=N2)CCC1)N6CCCC6 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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