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Biological Activity
PF 06465469 is a potent the nonreceptor tyrosine kinase Itk (IL-2 inducible T-cell kinase) inhibitor. It also inhibits BTK.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.1 mL | 95.49 mL | 190.97 mL |
| 0.5 mM | 3.82 mL | 19.1 mL | 38.19 mL |
| 1 mM | 1.91 mL | 9.55 mL | 19.1 mL |
| 5 mM | 0.38 mL | 1.91 mL | 3.82 mL |
*The above data is based on the productmolecular weight 523.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17190 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1407966-77-1 |
| Formula | C30H33N7O2 |
| M. Wt | 523.63 |
| Purity | >98% |
| Synonyms | PF06465469, PF-06465469 |
| SMILES | O=C(NC1=CC=C(C(C)C)C(C)=C1)C2=CC=CC(C3=NN([C@H]4CN(C(C=C)=O)CCC4)C5=NC=NC(N)=C53)=C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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