PF-514273 is a highly selective antagonist of the cannabinoid-1 receptor (CB1), exhibiting an IC50 of 1 nM. This compound demonstrates notable efficacy in reducing food intake in murine models, making it a valuable tool for obesity research. PF-514273 can be utilized to explore the role of CB1 signaling in appetite regulation and related metabolic disorders.
PF-514273 is a highly selective antagonist of the cannabinoid-1 receptor (CB1), exhibiting an IC50 of 1 nM. This compound demonstrates notable efficacy in reducing food intake in murine models, making it a valuable tool for obesity research. PF-514273 can be utilized to explore the role of CB1 signaling in appetite regulation and related metabolic disorders.
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