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PF-CBP1 is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.04 mL | 95.22 mL | 190.45 mL |
| 0.5 mM | 3.81 mL | 19.04 mL | 38.09 mL |
| 1 mM | 1.9 mL | 9.52 mL | 19.04 mL |
| 5 mM | 0.38 mL | 1.9 mL | 3.81 mL |
*The above data is based on the productmolecular weight 525.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A15876 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 525.08 |
| Formula | C29H36N4O3.HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1962928-21-7 |
| Synonyms | PF-CBP-1, PF-CBP 1, PF-06670910, PF 06670910, PF06670910 |
| SMILES | CCCOC1=CC=C(CCC2=NC3=CC(C4=C(C)ON=C4C)=CC=C3N2CCN5CCOCC5)C=C1 |
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