PG 01

Catalog No.: A18315

CFTR potentiator

PG 01

PG 01 Chemical Structure

CAS NO. 853138-65-5

PG 01 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. PG 01 is effective on G970R although with a significant decrease in potency relative to E193K and δF508.

Availability: In stock

Package Price Qty
5 mg
$150.00
10 mg
$280.00
50 mg
$650.00
100 mg
$1,200.00
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Biological Activity

PG 01 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. PG 01 is effective on G970R although with a significant decrease in potency relative to E193K and δF508.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.75 mL 113.75 mL 227.51 mL
0.5 mM 4.55 mL 22.75 mL 45.5 mL
1 mM 2.28 mL 11.38 mL 22.75 mL
5 mM 0.46 mL 2.28 mL 4.55 mL

*The above data is based on the productmolecular weight 439.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18315
Actions Potentiator
M. Wt 439.55
Formula C28H29N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 853138-65-5
Synonyms PG01, PG-01
SMILES O=C(C(C2=CC=CC=C2)N(C)C(CC3=CNC4=C3C=CC=C4)=O)NC1=CC=C(C(C)C)C=C1

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