Phe-Lys(Fmoc)-PAB is a cathepsin-cleavable linker designed for use in antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic payloads upon internalization, enhancing therapeutic efficacy. Its application is particularly valuable in targeted cancer therapies, where precise control over drug release is crucial for minimizing off-target effects and improving patient outcomes.
Phe-Lys(Fmoc)-PAB is a cathepsin-cleavable linker designed for use in antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic payloads upon internalization, enhancing therapeutic efficacy. Its application is particularly valuable in targeted cancer therapies, where precise control over drug release is crucial for minimizing off-target effects and improving patient outcomes.
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