Pittsburgh Compound B (PiB) is a targeted β-amyloid (Aβ) binder, designed as a PET tracer for the visualization of Aβ deposition in the brain. It exhibits a high affinity for Aβ(1-40) fibrils with a Ki value of 678.4 nM. The compound can be modified using click chemistry, allowing for the development of fluorescent conjugates for applications in fluorescence imaging and ultrastructural studies. Pittsburgh Compound B is particularly relevant for research focusing on Alzheimer's disease and the characterization of Aβ complexes.
Pittsburgh Compound B (PiB) is a targeted β-amyloid (Aβ) binder, designed as a PET tracer for the visualization of Aβ deposition in the brain. It exhibits a high affinity for Aβ(1-40) fibrils with a Ki value of 678.4 nM. The compound can be modified using click chemistry, allowing for the development of fluorescent conjugates for applications in fluorescence imaging and ultrastructural studies. Pittsburgh Compound B is particularly relevant for research focusing on Alzheimer's disease and the characterization of Aβ complexes.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
