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ɛPKC(85–92),Myristoylated

Catalog No.: A46195
PKC Activator
ɛPKC(85–92), Myristoylated is a cell-permeable peptide that activates Protein Kinase C (PKC) through myristoylation. This compound enhances nitric oxide (NO) release in cultured human umbilical vein endothelial cells (HUVECs), making it a valuable tool for investigating endothelial cell function and signaling pathways. Research applications include studies on vascular biology and the modulation of PKC activity in various physiological and pathological processes.
ɛPKC(85–92),Myristoylated 1072301-79-1 PKC Activator
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionɛPKC(85–92), Myristoylated is a cell-permeable peptide that activates Protein Kinase C (PKC) through myristoylation. This compound enhances nitric oxide (NO) release in cultured human umbilical vein endothelial cells (HUVECs), making it a valuable tool for investigating endothelial cell function and signaling pathways. Research applications include studies on vascular biology and the modulation of PKC activity in various physiological and pathological processes.
Product Information
Catalog NumA46195
FormulaC53H80N10O15
Molecular Weight1097.26
CAS Number1072301-79-1
Sequence{Myr}‐His-Asp-Ala-Pro-Ile-Gly-Tyr-Asp
Sequence shortening{Myr}‐HDAPIGYD
SMILESC(N[C@H](C(NCC(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)[C@H](CC)C)(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@H](CC3=CN=CN3)NC(CCCCCCCCCCCCC)=O)=O)CC(O)=O)=O)C)=O)CCC2
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TGF-β/Smad > Protein Kinase C (PKC)