PLX7904

Catalog No.: A15855
Raf inhibitor
PLX7904 is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.
Grouped product items
Product Name Price Stock Qty
PLX7904 5mg
Special Price $44.00 Regular Price $55.00
In stock
PLX7904 10mg
Special Price $72.00 Regular Price $90.00
In stock
PLX7904 25mg
Special Price $144.00 Regular Price $180.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription PLX7904 is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.
Targets
Target Value
Product Information
Catalog Num A15855
Formula C24H22F2N6O3S
Molecular Weight 512.53
CAS Number 1393465-84-3
SMILES O=C(C1=CNC2=NC=C(C3=CN=C(C4CC4)N=C3)C=C21)C5=C(F)C=CC(NS(=O)(N(CC)C)=O)=C5F
Synonyms PB04
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 87 mg/mL (169.75 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.51 mL 97.56 mL 195.11 mL
0.5 mM 3.9 mL 19.51 mL 39.02 mL
1 mM 1.95 mL 9.76 mL 19.51 mL
5 mM 0.39 mL 1.95 mL 3.9 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy PLX7904 | PLX7904 Supplier | purchase PLX7904 | PLX7904 cost | PLX7904 manufacturer | order PLX7904 | PLX7904 distributor | buy 1393465-84-3 | 1393465-84-3 Supplier | purchase 1393465-84-3 | 1393465-84-3 cost | 1393465-84-3 manufacturer | order 1393465-84-3 | 1393465-84-3 distributor