PM226 is a selective agonist of the cannabinoid receptor CB2 (Ki = 13 nM; EC50 = 39 nM) with minimal interaction with CB1 (Ki > 40 μM). This compound exhibits neuroprotective effects in both in vitro and in vivo studies, making it a valuable tool for research in neurodegenerative disorders. PM226 may also be applicable in exploring the therapeutic potential of cannabinoid receptors in various biological systems.
PM226 is a selective agonist of the cannabinoid receptor CB2 (Ki = 13 nM; EC50 = 39 nM) with minimal interaction with CB1 (Ki > 40 μM). This compound exhibits neuroprotective effects in both in vitro and in vivo studies, making it a valuable tool for research in neurodegenerative disorders. PM226 may also be applicable in exploring the therapeutic potential of cannabinoid receptors in various biological systems.
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