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Biological Activity
PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50 = 31 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.92 mL | 59.59 mL | 119.18 mL |
| 0.5 mM | 2.38 mL | 11.92 mL | 23.84 mL |
| 1 mM | 1.19 mL | 5.96 mL | 11.92 mL |
| 5 mM | 0.24 mL | 1.19 mL | 2.38 mL |
*The above data is based on the productmolecular weight 839.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16946 |
|---|---|
| Actions | Antagonist |
| CAS No. | 514814-49-4 |
| Formula | C45H62N10O6 |
| M. Wt | 839.05 |
| Purity | >98% |
| Synonyms | PMX205, PMX 205 |
| SMILES | O=C([C@]([H])(CC1=CNC2=C1C=CC=C2)NC([C@@H](CC3CCCCC3)NC([C@]4(N5CCC4)[H])=O)=O)N[C@@H](CCCNC(N)=N)C(NCCC[C@@]([H])(C5=O)NC(CCC6=CC=CC=C6)=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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