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Biological Activity
Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, notably Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
| In vitro | DMSO | 92 mg/mL (86.36 mM) | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.39 mL | 46.94 mL | 93.88 mL |
| 0.5 mM | 1.88 mL | 9.39 mL | 18.78 mL |
| 1 mM | 0.94 mL | 4.69 mL | 9.39 mL |
| 5 mM | 0.19 mL | 0.94 mL | 1.88 mL |
*The above data is based on the productmolecular weight 1065.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11113 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 135575-42-7 |
| Formula | C50H80N8O17 |
| M. Wt | 1065.2 |
| Purity | >98% |
| SMILES | O=C(N1[C@@]([H])([C@H](CC1)O)C(N[C@H](O)[C@H](O)C[C@H](NC(CCCCCCCC[C@H](C[C@H](CC)C)C)=O)C(NC2[C@@H](C)O)=O)=O)[C@]([H])([C@@H](CC(N)=O)O)NC(C([C@@H]([C@@H](O)C3=CC=C(C=C3)O)O)NC([C@]4([H])C[C@H](CN4C2=O)O)=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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