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Pneumocandin B0

Catalog No.: A11113

β-1,3-Glucan Synthase Inhibitor

Pneumocandin B0

Pneumocandin B0 Chemical Structure

CAS NO. 135575-42-7

Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, notably Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.

Availability: In stock

Package Price Qty
5 mg
$66.00
10 mg
$99.00
25 mg
$198.00
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Biological Activity

Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, notably Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
In vitro DMSO 92 mg/mL (86.36 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.39 mL 46.94 mL 93.88 mL
0.5 mM 1.88 mL 9.39 mL 18.78 mL
1 mM 0.94 mL 4.69 mL 9.39 mL
5 mM 0.19 mL 0.94 mL 1.88 mL

*The above data is based on the productmolecular weight 1065.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11113
Actions Inhibitor
CAS No. 135575-42-7
Formula C50H80N8O17
M. Wt 1065.2
Purity >98%
SMILES O=C(N1[C@@]([H])([C@H](CC1)O)C(N[C@H](O)[C@H](O)C[C@H](NC(CCCCCCCC[C@H](C[C@H](CC)C)C)=O)C(NC2[C@@H](C)O)=O)=O)[C@]([H])([C@@H](CC(N)=O)O)NC(C([C@@H]([C@@H](O)C3=CC=C(C=C3)O)O)NC([C@]4([H])C[C@H](CN4C2=O)O)=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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