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Biological Activity
PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 uM without affecting NF-kappaB transcription (up to 200 μM) or thioredoxin (up to 200 μM).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.91 mL | 124.57 mL | 249.15 mL |
0.5 mM | 4.98 mL | 24.91 mL | 49.83 mL |
1 mM | 2.49 mL | 12.46 mL | 24.91 mL |
5 mM | 0.5 mL | 2.49 mL | 4.98 mL |
*The above data is based on the productmolecular weight 401.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16305 |
---|---|
Actions | Inhibitor |
CAS No. | 550368-41-7 |
Formula | C21H15N5O4 |
M. Wt | 401.37 |
Purity | >98% |
Synonyms | PNRI299, PNRI 299 |
SMILES | C1C(=O)C=C(N2N1C(=O)N(C2=O)C3=CC=CC(=C3)C#N)C(=O)NCC4=CC=CC=C4 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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