PNU-282987 free base
nAChR agonist
Important Notice: For research use only. We do not sell to patients.
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nAChR agonist
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | PNU 282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM). |
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Catalog Num | A22518 |
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Formula | C14H17ClN2O |
Molecular Weight | 264.75 |
CAS Number | 711085-63-1 |
SMILES | O=C(N[C@H]1CN2CCC1CC2)C3=CC=C(Cl)C=C3 |
Synonyms | PNU-282987, PNU 282987, PNU282987. |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2