PNZ5

Catalog No.: A12764

BET inhibitor

PNZ5

PNZ5 Chemical Structure

CAS NO. 1629277-36-6

PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1).

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.41 mL 157.05 mL 314.1 mL
0.5 mM 6.28 mL 31.41 mL 62.82 mL
1 mM 3.14 mL 15.7 mL 31.41 mL
5 mM 0.63 mL 3.14 mL 6.28 mL

*The above data is based on the productmolecular weight 318.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12764
Actions Inhibitor
M. Wt 318.37
Formula C20H18N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1629277-36-6
Synonyms PNZ-5, PNZ 5
SMILES CN1C(C2=CC=C(C3=C(C)ON=C3C)C=C2[[email protected]@]1(C4=CC=CC=C4)[H])=O

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