Pomalidomid-C6-PEG3-butyl-N3 is a crosslinker-E3 ligase ligand conjugate designed for click chemistry applications. This reagent features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and ring strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. Pomalidomid-C6-PEG3-butyl-N3 serves as an essential building block for the development of proteolysis-targeting chimeras (PROTACs) and targeted protein degraders, facilitating advancements in targeted protein degradation research.
Pomalidomid-C6-PEG3-butyl-N3 is a crosslinker-E3 ligase ligand conjugate designed for click chemistry applications. This reagent features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and ring strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. Pomalidomid-C6-PEG3-butyl-N3 serves as an essential building block for the development of proteolysis-targeting chimeras (PROTACs) and targeted protein degraders, facilitating advancements in targeted protein degradation research.
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