Pomalidomide 4'-alkylC8-acid

Catalog No.: A80172
E3 Ubiquitinase Ligand-Linker Conjugate
Pomalidomide 4'-alkylC8-acid is an E3 ubiquitin ligase ligand-linker conjugate featuring Pomalidomide, a third-generation immunomodulator. This compound functions as a molecular glue, binding to the E3 ligase cereblon and facilitating the degradation of the essential Ikaros transcription factor. It is valuable for research applications related to targeted protein degradation and understanding the regulatory mechanisms of immune response.
Grouped product items
Size Price Stock Qty
1mg
$55.00
In stock
5mg
$140.00
In stock
10mg
$230.00
In stock
25mg
$410.00
In stock
50mg
$720.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPomalidomide 4'-alkylC8-acid is an E3 ubiquitin ligase ligand-linker conjugate featuring Pomalidomide, a third-generation immunomodulator. This compound functions as a molecular glue, binding to the E3 ligase cereblon and facilitating the degradation of the essential Ikaros transcription factor. It is valuable for research applications related to targeted protein degradation and understanding the regulatory mechanisms of immune response.
Product Information
Catalog NumA80172
FormulaC22H27N3O6
Molecular Weight429.47
CAS Number2305936-70-1
SMILESO=C(O)CCCCCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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