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Pomalidomide-5'-C8-acid

Catalog No.: A80182
E3 ligase ligand-linker conjugate
Pomalidomide-5'-C8-acid is an E3 ligase ligand-linker conjugate featuring a cereblon (CRBN) ligand derived from Pomalidomide. This compound is designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating targeted protein degradation. Its unique structure allows for efficient engagement with E3 ligases, making it a valuable tool in molecular biology and therapeutic research.
Pomalidomide-5'-C8-acid 2682112-09-8 E3 ligase ligand-linker conjugate
Grouped product items
Size Price Stock Qty
5mg
$140.00
In stock
10mg
$230.00
In stock
25mg
$460.00
In stock
50mg
$720.00
In stock
100mg
$1,125.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPomalidomide-5'-C8-acid is an E3 ligase ligand-linker conjugate featuring a cereblon (CRBN) ligand derived from Pomalidomide. This compound is designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating targeted protein degradation. Its unique structure allows for efficient engagement with E3 ligases, making it a valuable tool in molecular biology and therapeutic research.
Product Information
Catalog NumA80182
FormulaC22H27N3O6
Molecular Weight429.47
CAS Number2682112-09-8
SMILESO=C(CCCCCCCCNC1=CC=C2C(N(C3C(NC(CC3)=O)=O)C(C2=C1)=O)=O)O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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PROTAC > E3 Ligase Ligand-Linker Conjugate