Pomalidomide 5'-pip-acid is a molecular glue that functions as a dual-target PROTAC degrader, specifically targeting CBP/p300 and BRD4. It exhibits significant antiproliferative activity against cancer cells, with an IC50 value of 2.73 nM. This compound is particularly relevant for research in prostate and colorectal cancer, offering a valuable tool for investigating targeted degradation pathways in oncogenesis.
Pomalidomide 5'-pip-acid is a molecular glue that functions as a dual-target PROTAC degrader, specifically targeting CBP/p300 and BRD4. It exhibits significant antiproliferative activity against cancer cells, with an IC50 value of 2.73 nM. This compound is particularly relevant for research in prostate and colorectal cancer, offering a valuable tool for investigating targeted degradation pathways in oncogenesis.
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