Pomalidomide-amido-PEG3-C2-NH2 is an E3 ligase ligand-linker conjugate that utilizes a Pomalidomide-derived cereblon ligand coupled with a three-unit polyethylene glycol (PEG) linker. This compound is designed for applications in PROTAC (proteolysis-targeting chimeras) technology, facilitating targeted protein degradation. Its unique structure enables selective engagement with the CRBN E3 ubiquitin ligase, supporting research into protein modulation and therapeutic interventions in various diseases.
Pomalidomide-amido-PEG3-C2-NH2 is an E3 ligase ligand-linker conjugate that utilizes a Pomalidomide-derived cereblon ligand coupled with a three-unit polyethylene glycol (PEG) linker. This compound is designed for applications in PROTAC (proteolysis-targeting chimeras) technology, facilitating targeted protein degradation. Its unique structure enables selective engagement with the CRBN E3 ubiquitin ligase, supporting research into protein modulation and therapeutic interventions in various diseases.
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