Pomalidomide-C2-amide-C4-Br is an E3 ligase ligand-linker conjugate that incorporates a Pomalidomide-based ligand targeting cereblon (CRBN). This compound is utilized in the synthesis of PROTACs (proteolysis-targeting chimeras), enabling targeted protein degradation and advancing studies in cellular regulation and therapeutic development. The incorporation of the linker facilitates the conjugation of E3 ligase components for efficient protein modulation.
Pomalidomide-C2-amide-C4-Br is an E3 ligase ligand-linker conjugate that incorporates a Pomalidomide-based ligand targeting cereblon (CRBN). This compound is utilized in the synthesis of PROTACs (proteolysis-targeting chimeras), enabling targeted protein degradation and advancing studies in cellular regulation and therapeutic development. The incorporation of the linker facilitates the conjugation of E3 ligase components for efficient protein modulation.
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