Pomalidomide-CO-C5-azide is a bioorthogonal ligand designed for E3 ligase interaction. This compound enables the synthesis of proteolysis-targeting chimeras (PROTACs), which demonstrate promising anticancer activity. It serves as a valuable tool for researchers developing targeted therapies that utilize the ubiquitin-proteasome system to selectively degrade oncogenic proteins.
Pomalidomide-CO-C5-azide is a bioorthogonal ligand designed for E3 ligase interaction. This compound enables the synthesis of proteolysis-targeting chimeras (PROTACs), which demonstrate promising anticancer activity. It serves as a valuable tool for researchers developing targeted therapies that utilize the ubiquitin-proteasome system to selectively degrade oncogenic proteins.
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