Pomalidomide-PEG1-azide is an E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand along with a PEG1 linker. This compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Pomalidomide-PEG1-azide can be utilized in the design and synthesis of PROTACs, such as the BRD4 Degrader-1, facilitating targeted protein degradation research.
Pomalidomide-PEG1-azide is an E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand along with a PEG1 linker. This compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Pomalidomide-PEG1-azide can be utilized in the design and synthesis of PROTACs, such as the BRD4 Degrader-1, facilitating targeted protein degradation research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
