Pomalidomide-PEG1-C2-COOH is an E3 ligase ligand-linker conjugate that combines the cereblon-targeting properties of Pomalidomide with a one-unit polyethylene glycol (PEG) linker. This compound is designed for use in PROTAC (Proteolysis Targeting Chimeras) applications, enabling targeted protein degradation. Its structure facilitates the selective recruitment of E3 ligases, thus expanding the toolkit for researchers studying cellular protein regulation and therapeutic interventions.
Pomalidomide-PEG1-C2-COOH is an E3 ligase ligand-linker conjugate that combines the cereblon-targeting properties of Pomalidomide with a one-unit polyethylene glycol (PEG) linker. This compound is designed for use in PROTAC (Proteolysis Targeting Chimeras) applications, enabling targeted protein degradation. Its structure facilitates the selective recruitment of E3 ligases, thus expanding the toolkit for researchers studying cellular protein regulation and therapeutic interventions.
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