Pomalidomide-PEG1-NH2 hydrochloride is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound incorporates pomalidomide, a well-characterized E3 ligase ligand, fused with a PEGylated crosslinker featuring a terminal amine. It facilitates the conjugation to carboxyl groups on target ligands, enhancing specificity and stability in biochemical assays and research involving the modulation of protein degradation pathways.
Pomalidomide-PEG1-NH2 hydrochloride is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound incorporates pomalidomide, a well-characterized E3 ligase ligand, fused with a PEGylated crosslinker featuring a terminal amine. It facilitates the conjugation to carboxyl groups on target ligands, enhancing specificity and stability in biochemical assays and research involving the modulation of protein degradation pathways.
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