Pomalidomide-PEG2-Tos is an E3 ligase ligand-linker conjugate that incorporates a cereblon ligand connected through a diethylene glycol (PEG2) spacer. This compound facilitates targeted protein degradation by recruiting E3 ligases, enabling the selective degradation of specific substrates. It is especially useful in research focused on the modulation of protein levels and the development of targeted therapeutics for various diseases, including cancer.
Pomalidomide-PEG2-Tos is an E3 ligase ligand-linker conjugate that incorporates a cereblon ligand connected through a diethylene glycol (PEG2) spacer. This compound facilitates targeted protein degradation by recruiting E3 ligases, enabling the selective degradation of specific substrates. It is especially useful in research focused on the modulation of protein levels and the development of targeted therapeutics for various diseases, including cancer.
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