Pomalidomide-PEG3-C2-NH2 hydrochloride

Catalog No.: A80003
E3 Ligase Ligand-Linker Conjugates
Pomalidomide-PEG3-C2-NH2 hydrochloride is an E3 ligase ligand-linker conjugate that combines the Pomalidomide-derived cereblon ligand with a polyethylene glycol (PEG) linker. This compound facilitates targeted protein degradation through the PROTAC (proteolysis targeting chimera) technology by promoting the recruitment of E3 ubiquitin ligases. It is suitable for applications in investigations of protein turnover and cellular signaling pathways.
Grouped product items
Size Price Stock Qty
25mg
$105.00
In stock
50mg
$165.00
In stock
100mg
$240.00
In stock
250mg
$420.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPomalidomide-PEG3-C2-NH2 hydrochloride is an E3 ligase ligand-linker conjugate that combines the Pomalidomide-derived cereblon ligand with a polyethylene glycol (PEG) linker. This compound facilitates targeted protein degradation through the PROTAC (proteolysis targeting chimera) technology by promoting the recruitment of E3 ubiquitin ligases. It is suitable for applications in investigations of protein turnover and cellular signaling pathways.
Product Information
Catalog NumA80003
FormulaC21H29ClN4O7
Molecular Weight484.93
CAS Number2446474-09-3
SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCN)=O.[H]Cl
SynonymsCereblon Ligand-Linker Conjugates 5 hydrochloride; E3 ligase Ligand-Linker Conjugates 30 hydrochloride
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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