Poziotinib

Catalog No.: A13044
EGFR inhibitor
Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
Poziotinib 5mg
$70.00
In stock
Poziotinib 10mg
$100.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Poziotinib has been cited by 1 publications
  • Ikei S Kobayashi, .et al. , Cells, 2021, 10(12): 3561 PMID: 34944068
  • Biological Activity
    Discription Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
    Targets
    Target Value
    Product Information
    Catalog Num A13044
    Formula C23H21Cl2FN4O3
    Molecular Weight 491.34
    CAS Number 1092364-38-9
    SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C
    Synonyms HM781-36B, NOV120101, NOV-120101, NOV 120101
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 84 mg/mL (170.96 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.35 mL 101.76 mL 203.53 mL
    0.5 mM 4.07 mL 20.35 mL 40.71 mL
    1 mM 2.04 mL 10.18 mL 20.35 mL
    5 mM 0.41 mL 2.04 mL 4.07 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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