Poziotinib

Name: Poziotinib
SKU: A13044
Price: 56 USD
Rating: 5 (1 reviews)

Catalog No.: A13044

EGFR inhibitor

Adooq's Poziotinib has been cited by 1 publications

Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.

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Grouped product items
Product Name	Price	Stock
Poziotinib 5mg	Special Price $56.00 Regular Price $70.00	In stock
Poziotinib 10mg	Special Price $80.00 Regular Price $100.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Poziotinib has been cited by 1 publications

Ikei S Kobayashi, .et al. , Cells, 2021, 10(12): 3561 PMID: 34944068

Biological Activity

Discription

Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.

Targets

Target	Value

Product Information

Catalog Num	A13044
Formula	C23H21Cl2FN4O3
Molecular Weight	491.34
CAS Number	1092364-38-9
SMILES	COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C
Synonyms	HM781-36B, NOV120101, NOV-120101, NOV 120101
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	84 mg/mL (170.96 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.35 mL	101.76 mL	203.53 mL
0.5 mM	4.07 mL	20.35 mL	40.71 mL
1 mM	2.04 mL	10.18 mL	20.35 mL
5 mM	0.41 mL	2.04 mL	4.07 mL

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