pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

Catalog No.: A28572
EGFR Substrate
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide that serves as a substrate for the epidermal growth factor receptor (EGFR). This product is utilized for the evaluation of EGFR kinase inhibitors through the quantification of phosphorylated substrates, aiding in the exploration of signaling pathways and potential therapeutic applications in cancer research. Its precise autophosphorylation site makes it an essential tool for discerning kinase activity in various biological assays.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionpp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide that serves as a substrate for the epidermal growth factor receptor (EGFR). This product is utilized for the evaluation of EGFR kinase inhibitors through the quantification of phosphorylated substrates, aiding in the exploration of signaling pathways and potential therapeutic applications in cancer research. Its precise autophosphorylation site makes it an essential tool for discerning kinase activity in various biological assays.
Product Information
Catalog NumA28572
FormulaC66H110N23O26P
Molecular Weight1672.69
CAS Number176042-83-4
SequenceArg-Arg-Leu-Ile-Glu-Asp-Asn-Glu-{pTyr}-Thr-Ala-Arg-Gly
Sequence shorteningRRLIEDNE-{pTyr}-TARG
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O
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