PPARγ Agonist 4 (Compound 18b) is a potent and selective agonist targeting the peroxisome proliferator-activated receptor gamma (PPARγ). This compound demonstrates notable antitumor activity specifically in combination with Imatinib, highlighting its potential in enhancing therapeutic effects in resistant tumor models. Furthermore, PPARγ Agonist 4 is non-cytotoxic to both resistant and non-resistant cell lines, making it a valuable tool for research applications aimed at understanding PPARγ modulation in cancer therapy.
PPARγ Agonist 4 (Compound 18b) is a potent and selective agonist targeting the peroxisome proliferator-activated receptor gamma (PPARγ). This compound demonstrates notable antitumor activity specifically in combination with Imatinib, highlighting its potential in enhancing therapeutic effects in resistant tumor models. Furthermore, PPARγ Agonist 4 is non-cytotoxic to both resistant and non-resistant cell lines, making it a valuable tool for research applications aimed at understanding PPARγ modulation in cancer therapy.
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