PPARγ-IN-5 is a selective inhibitor of PPARγ, a key regulator of adipocyte differentiation and lipid metabolism. This compound effectively reduces lipid accumulation in hepatocytes, demonstrating minimal cytotoxicity at concentrations up to 400 µM in HepG2 cells. PPARγ-IN-5 is suitable for investigations into non-alcoholic fatty liver disease and related metabolic disorders.
PPARγ-IN-5 is a selective inhibitor of PPARγ, a key regulator of adipocyte differentiation and lipid metabolism. This compound effectively reduces lipid accumulation in hepatocytes, demonstrating minimal cytotoxicity at concentrations up to 400 µM in HepG2 cells. PPARγ-IN-5 is suitable for investigations into non-alcoholic fatty liver disease and related metabolic disorders.
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