PRMT5-MTA-IN-7

Name: PRMT5-MTA-IN-7
Brand: Adooq Bioscience
SKU: A26699
Rating: 5 (288 reviews)

Catalog No.: A26699

PRMT5-MTA Inhibitor

PRMT5-MTA-IN-7 is a selective inhibitor of the PRMT5-MTA complex, demonstrating a KD of 236 nM for PRMT5-MTA and 2.84 μM for PRMT5-SAM. It exhibits IC50 values of 4.08 μM and 13.6 μM for these targets, respectively. This compound selectively inhibits the proliferation of MTAP-deficient cancer cells, making it a valuable tool for research in colon cancer and related studies.

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PRMT5-MTA-IN-7 303969-88-2 PRMT5-MTA Inhibitor

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Biological Activity

Description	PRMT5-MTA-IN-7 is a selective inhibitor of the PRMT5-MTA complex, demonstrating a KD of 236 nM for PRMT5-MTA and 2.84 μM for PRMT5-SAM. It exhibits IC50 values of 4.08 μM and 13.6 μM for these targets, respectively. This compound selectively inhibits the proliferation of MTAP-deficient cancer cells, making it a valuable tool for research in colon cancer and related studies.

Product Information

Catalog Num	A26699
Formula	C17H20N4O4S
Molecular Weight	376.43
CAS Number	303969-88-2
SMILES	CC(C=C1)=CC=C1CN2C(SCC(O)CO)=NC3=C2C(NC(N3C)=O)=O

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