Pro8-Oxytocin is a modified oxytocin (OXT) ligand that exhibits enhanced potency and efficacy at primate oxytocin receptors (OXTR) compared to Leu8-Oxytocin. This compound demonstrates significantly stronger behavioral effects, making it a valuable tool in neuropharmacology research. Additionally, Pro8-Oxytocin shows a lower efficacy than vasopressin at human AVPR1a receptors while producing a higher efficacy at marmoset AVPR1a receptors, positioning it as an important reagent for studying receptor specificity and ligand-receptor interactions.
Pro8-Oxytocin is a modified oxytocin (OXT) ligand that exhibits enhanced potency and efficacy at primate oxytocin receptors (OXTR) compared to Leu8-Oxytocin. This compound demonstrates significantly stronger behavioral effects, making it a valuable tool in neuropharmacology research. Additionally, Pro8-Oxytocin shows a lower efficacy than vasopressin at human AVPR1a receptors while producing a higher efficacy at marmoset AVPR1a receptors, positioning it as an important reagent for studying receptor specificity and ligand-receptor interactions.
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