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Probestin

Catalog No.: A69441
Aminopeptidase N Inhibitor
Probestin is a potent inhibitor of aminopeptidase N (APN), derived from the bacterium Streptomyces cyanogens MH663-2F6. This compound exhibits significant biological activity by selectively blocking APN activity, leading to the modulation of various physiological processes. Probestin is valuable for research applications focused on studying the role of APN in cancer, inflammation, and immune response pathways.
Probestin 123652-87-9 Aminopeptidase N Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionProbestin is a potent inhibitor of aminopeptidase N (APN), derived from the bacterium Streptomyces cyanogens MH663-2F6. This compound exhibits significant biological activity by selectively blocking APN activity, leading to the modulation of various physiological processes. Probestin is valuable for research applications focused on studying the role of APN in cancer, inflammation, and immune response pathways.
Product Information
Catalog NumA69441
FormulaC26H38N4O6
Molecular Weight502.60
CAS Number123652-87-9
SMILESO=C(O)[C@H]1N(C([C@H]2N(C([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC3=CC=CC=C3)=O)=O)CCC2)=O)CCC1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Proteases > Aminopeptidase