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Promethazine-d4

Catalog No.: A33960
H1 Receptor Antagonist
Promethazine-d4 is a deuterated form of promethazine, functioning primarily as an H1 receptor antagonist. This compound exhibits antihistamine, sedative, antiemetic, anticholinergic, and anti-motion sickness activities. It is widely utilized in research applications focused on histamine-related disorders and the pharmacological study of sedation and motion sickness.
Promethazine-d4 1173147-64-2 H1 Receptor Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPromethazine-d4 is a deuterated form of promethazine, functioning primarily as an H1 receptor antagonist. This compound exhibits antihistamine, sedative, antiemetic, anticholinergic, and anti-motion sickness activities. It is widely utilized in research applications focused on histamine-related disorders and the pharmacological study of sedation and motion sickness.
Product Information
Catalog NumA33960
FormulaC17H16D4N2S
Molecular Weight288.44
CAS Number1173147-64-2
SMILES[2H]C1=CC2=C(N(C3=C(S2)C=C(C=C3[2H])[2H])CC(N(C)C)C)C([2H])=C1
Synonyms(±)-Promethazine-d4; N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine-d4
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Histamine Receptors