PSB-1901 is a potent antagonist of the A2B adenosine receptor (A2BAR), exhibiting inhibition constants (Kis) of 0.0835 nM for human and 0.131 nM for mouse A2BARs. This compound is instrumental in the investigation of adenosine signaling pathways and their implications in cancer research. Its high selectivity and potency make it a valuable tool for elucidating the role of A2BAR in tumor biology and developing potential therapeutic strategies.
PSB-1901 is a potent antagonist of the A2B adenosine receptor (A2BAR), exhibiting inhibition constants (Kis) of 0.0835 nM for human and 0.131 nM for mouse A2BARs. This compound is instrumental in the investigation of adenosine signaling pathways and their implications in cancer research. Its high selectivity and potency make it a valuable tool for elucidating the role of A2BAR in tumor biology and developing potential therapeutic strategies.
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