PSN 375963 is a potent agonist of the GPR119 receptor, demonstrating EC50 values of 8.4 μM for human and 7.9 μM for mouse GPR119. This compound exhibits comparable potency to the endogenous agonist oleoylethanolamide (OEA). PSN 375963 may serve as a valuable tool for research into metabolic disorders and obesity by elucidating the role of GPR119 in glucose homeostasis and insulin secretion.
PSN 375963 is a potent agonist of the GPR119 receptor, demonstrating EC50 values of 8.4 μM for human and 7.9 μM for mouse GPR119. This compound exhibits comparable potency to the endogenous agonist oleoylethanolamide (OEA). PSN 375963 may serve as a valuable tool for research into metabolic disorders and obesity by elucidating the role of GPR119 in glucose homeostasis and insulin secretion.
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