PTC124 (Ataluren)

PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.
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Product Name Price Stock Qty
PTC124 10mg
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PTC124 25mg
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PTC124 50mg
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PTC124 100mg
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PTC124 (Ataluren) 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's PTC124 (Ataluren) has been cited by 2 publications
  • L Kadunc, .et al. , FEBS Lett, 2020, May 13 PMID: 32401336
  • Caspi M, .et al. , J Mol Med (Berl), 2016, Apr;94(4):469-82 PMID: 26620677
  • Biological Activity
    Discription PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.
    Target Value
    Product Information
    Catalog Num A10758
    Formula C15H9FN2O3
    Molecular Weight 284.2
    CAS Number 775304-57-9
    SMILES C1=CC=C(C(=C1)C2=NC(=NO2)C3=CC(=CC=C3)C(=O)O)F

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 55 mg/mL (193.49 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 35.19 mL 175.93 mL 351.86 mL
    0.5 mM 7.04 mL 35.19 mL 70.37 mL
    1 mM 3.52 mL 17.59 mL 35.19 mL
    5 mM 0.7 mL 3.52 mL 7.04 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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