PTC124 (Ataluren)

Catalog No.: A10758

CFTR inhibitor

PTC124 (Ataluren)

PTC124 (Ataluren) Chemical Structure

CAS NO. 775304-57-9

PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $40.00

Special Price $32.00

25 mg

Regular Price: $80.00

Special Price $64.00

50 mg

Regular Price: $120.00

Special Price $96.00

100 mg

Regular Price: $200.00

Special Price $160.00

10mM * 1mL in DMSO
$50.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.
Targets
CFTR (HEK293 cells)
In vitro (25°C) DMSO 57 mg/mL (200.53 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.19 mL 175.93 mL 351.86 mL
0.5 mM 7.04 mL 35.19 mL 70.37 mL
1 mM 3.52 mL 17.59 mL 35.19 mL
5 mM 0.7 mL 3.52 mL 7.04 mL

*The above data is based on the productmolecular weight 284.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10758
Actions Inhibitor
M. Wt 284.2
Formula C15H9FN2O3
Solubility DMSO>57mg/mL Water<1mg/mL Ethanol<1mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 775304-57-9
Synonyms PTC-124, PTC 124
SMILES C1=CC=C(C(=C1)C2=NC(=NO2)C3=CC(=CC=C3)C(=O)O)F

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