PU-H71

Catalog No.: A11130

Hsp90 Inhibitor

PU-H71

PU-H71 Chemical Structure

CAS NO. 873436-91-0

PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM).

Availability: Discontinuted

Package Price
5 mg
$60.00
10 mg
$85.00
25 mg
$160.00
50 mg
$300.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Kale S, .et al. HSP90 inhibitor PU-H71 increases radiosensitivity of breast cancer cells metastasized to visceral organs and alters the levels of inflammatory mediators, Naunyn Schmiedebergs Arch Pharmacol, 2019, Sep 14 PMID: 31522240
  • Hiroki Murano, .et al. A purine-type heat shock protein 90 inhibitor promotes the heat shock response in Arabidopsis, Plant Biotechnol Rep, 2017, 11:107–113

Biological Activity

PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM).
Targets
HSP90
51 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.52 mL 97.59 mL 195.17 mL
0.5 mM 3.9 mL 19.52 mL 39.03 mL
1 mM 1.95 mL 9.76 mL 19.52 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 512.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11130
Actions Inhibitor
M. Wt 512.37
Formula C18H21IN6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 873436-91-0
Synonyms PUH71
SMILES CC(C)NCCCN1C2=C(C(=NC=N2)N)N=C1SC3=C(C=C4C(=C3)OCO4)I

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