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PU-WS13

Grp94 Inhibitor

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Catalog No. A14129

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PU-WS13 5mg A14129-5
€61.75
PU-WS13 10mg A14129-10
€104.50
PU-WS13 25mg A14129-25
€209.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-WS13 is a cell-permeable inhibitor of Grp94 with EC50 of 220 nM.

PU-WS13

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Chemical Information

Catalog Num A14129
Actions Inhibitor
M. Wt 411.35
Formula C17H20Cl2N6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1454619-14-7
Synonyms PU-WS-13
SMILES CC(NCCCN1C2=NC=NC(N)=C2N=C1SC3=CC(Cl)=CC(Cl)=C3)C

Biological Activity

Description
PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-WS13 is a cell-permeable inhibitor of Grp94 with EC50 of 220 nM.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.31 mL 121.55 mL 243.1mL
0.5 mM 4.86 mL 24.31 mL 48.62 mL
1 mM 2.43 mL 12.16 mL 24.31 mL
5 mM 0.49 mL 2.43 mL 4.86 mL

*The above data is based on the productmolecular weight 411.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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