Pulrodemstat (hydrochloride) is a potent and selective reversible inhibitor of lysine-specific demethylase-1 (LSD1), exhibiting an IC50 value of 0.25 nM. This compound demonstrates minimal enzymatic inhibition of LSD2, MAO-A, and MAO-B, making it a highly specific agent. Pulrodemstat (hydrochloride) promotes differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells, showcasing significant anticancer activity. It serves as a valuable tool for research in cancer biology and therapeutic development.
Pulrodemstat (hydrochloride) is a potent and selective reversible inhibitor of lysine-specific demethylase-1 (LSD1), exhibiting an IC50 value of 0.25 nM. This compound demonstrates minimal enzymatic inhibition of LSD2, MAO-A, and MAO-B, making it a highly specific agent. Pulrodemstat (hydrochloride) promotes differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells, showcasing significant anticancer activity. It serves as a valuable tool for research in cancer biology and therapeutic development.
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