Pumafentrine is a potent orally active dual inhibitor of phosphodiesterase type 3 (PDE3) and phosphodiesterase type 4 (PDE4). It has demonstrated the ability to ameliorate clinical symptoms and reduce colonic TNFα production in murine models of Dextran sulphate sodium (DSS)-induced colitis. Pumafentrine is relevant for research in inflammation and gastrointestinal disorders, providing insights into therapeutic strategies targeting these pathways.
Pumafentrine is a potent orally active dual inhibitor of phosphodiesterase type 3 (PDE3) and phosphodiesterase type 4 (PDE4). It has demonstrated the ability to ameliorate clinical symptoms and reduce colonic TNFα production in murine models of Dextran sulphate sodium (DSS)-induced colitis. Pumafentrine is relevant for research in inflammation and gastrointestinal disorders, providing insights into therapeutic strategies targeting these pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
